This  summary  describes  an  article  published  in  the  medical  journal Frontiers  in  Oncology  in  September  2023.  The  article  reports  results  from  a  study  that  looked  at  breast  cancer  treatments for older patients aged 75 years or older. The study focused  on  a  type  of  cancer  called  HR+/HER2-  metastatic  breast   cancer.   HR+/HER2-   stands   for   hormone   receptor-positive/human  epidermal  growth  factor  receptor  2-negative.  This  study  evaluated  whether  older  patients  with  this  type  of  cancer  benefited  from  the  combination  of  two  medicines  –  palbociclib and an aromatase inhibitor – compared with taking an aromatase inhibitor alone.This Plain Language Summary of Publication article (PLSP) from Future Oncology summarises the results from a study that looked at breast cancer treatments for older patients aged 75 years or older. The study focused on a type of cancer called HR+/HER2- metastatic breast cancer and evaluated whether older patients with this type of cancer benefited from the combination of two medicines – palbociclib and an aromatase inhibitor – compared with taking an aromatase inhibitor alone.

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This PLSP is based on an articles called ‘Real-world treatment patterns and effectiveness of palbociclib plus an aromatase inhibitor in patients with metastatic breast cancer aged 75 years or older’. The article was published in the journal Frontiers in Oncology. 

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