The site will be unavailable from 11:00 PM GMT on Tuesday, 21 July 2026, until 4:00 AM GMT on Wednesday, 22 July 2026, due to scheduled maintenance.

cytokines and cell signaling

This is a summary of the results of 2 clinical studies that looked at a medicine called tezepelumab. Tezepelumab is approved in the United States of America (USA), the European Union (EU) and several other countries for the treatment of severe, uncontrolled asthma in people aged 12 and older. The results of these 2 studies, called PATHWAY and NAVIGATOR, formed the basis for tezepelumab’s approval for use. Tezepelumab is a type of biologic treatment called an antibody. It works by blocking a key first step in the body’s chain reaction leading to inflammation in the airways of people with severe asthma.The clinical studies were done to learn if tezepelumab can be used to treat people with severe, uncontrolled asthma and to find out about its safety. In both studies, tezepelumab was compared with the placebo

29th Sep 2023

A plain language summary of the PATHWAY and NAVIGATOR studies: tezepelumab for the treatment of severe asthma