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tepotinib

Sacituzumab govitecan (brand name: TRODELVY®) is a new treatment for certain types of advanced or metastatic breast cancer. One common type of breast cancer has at least 1 of 2 hormone receptors (HR positive) and does not have human epidermal growth factor 2 (HER2 negative). The HR and HER2 receptors are known to influence how severe a case of breast cancer is. Certain treatments will only work if a specific receptor is present on breast cancer cells. HR-positive/HER2-negative advanced or metastatic breast cancer can be treated with sacituzumab govitecan. This is a summary of the results of the TROPiCS-02 study. This study compared sacituzumab govitecan with standard chemotherapy in participants with HR-positive/HER2-negative advanced or metastatic breast cancer.
25th Jan 2024

The TROPiCS-02 study: a plain language summary on the effectiveness of sacituzumab govitecan in treating HR-positive/HER2-negative breast cancer

This plain language summary provides an overview of two of the main clinical studies that led to tepotinib’s approval, the phase I first-in-human study and the phase II VISION study
23rd May 2023

Plain Language Summary: tepotinib, a treatment for a subtype of non-small cell lung cancer called MET exon 14 skipping

20th Dec 2021

Plain language summary of INSIGHT 2: a study to learn about the effects and safety of tepotinib plus osimertinib in patents with a type of non-small cell lung cancer

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