The site will be unavailable from 11:00 PM GMT on Tuesday, 21 July 2026, until 4:00 AM GMT on Wednesday, 22 July 2026, due to scheduled maintenance.

This Plain Language Summary of Publication article (PLSP) from Current Medical Research & Opinion, highlights the OPTIMIZE trial, which evaluated tenapanor for managing high phosphate levels in dialysis patients. Despite treatments like dialysis, phosphate binders, and low-phosphate diets, many patients struggle to control phosphate levels. The study explored tenapanor’s effectiveness and different ways to start treatment.

Visit the site using this link to read the article.

This PLSP is based on an article called ‘Effectiveness of tenapanor for treating hyperphosphatemia in patients receiving dialysis: a plain language summary of the OPTIMIZE study’ and was published in Kidney 360. 

Visit ASN using the link to read the original article.