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Bladder, Kidney and Genitals

25th Feb 2026

Plain language summary of pegcetacoplan therapy in kidney transplant patients with C3G or primary IC-MPGN from the NOBLE study

25th Feb 2026

Plain language summary of sparsentan clinical trial findings in patients with focal segmental glomerulosclerosis

25th Feb 2026

Long-term outcomes of atacicept therapy in IgA nephropathy patients: a plain language summary

1st Dec 2025

Kidney function in Fabry patients plain language summary: agalsidase beta treatment

22nd Sep 2025

LOCK IT-100 study: A plain language summary of the taurolidine/heparin catheter lock solution

16th Sep 2025

Plain language summary: Global Registry data shows patients with aHUS can safely and effectively change from eculizumab to ravulizumab treatment

28th Aug 2025

Examining empagliflozin’s safety profile across four clinical trials: a plain language summary

25th Jun 2025

Plain language summary: benefits of SGLT2 inhibitor medications for people living with chronic kidney disease

24th Feb 2025

Plain language summary: effectiveness and safety of gepotidacin, a new oral antibiotic, versus nitrofurantoin, a commonly used antibiotic, for treating uncomplicated urinary tract infections

11th Feb 2025

A plain language summary of a study on long-term outcomes in IgA nephropathy patients from the UK Rare Kidney Diseases Registry (RaDaR)

17th Jan 2025

Evaluating tenapanor for managing hyperphosphatemia in dialysis patients: a plain language summary of the OPTIMIZE study

This summary describes the results from an additional (or post hoc) analysis of the TITAN study. The TITAN study looked at whether the prostate cancer treatment apalutamide could be used to treat individuals with metastatic castration-sensitive prostate cancer (or mCSPC).
22nd Jan 2024

The TITAN study: a plain language summary looking at how PSA decline with apalutamide therapy is associated with longer survival and improved outcomes in people with metastatic prostate cancer

18th Jan 2024

Plain language summary: looking at the enfortumab vedotin plus pembrolizumab treatment combination for untreated locally advanced or metastatic urothelial cancer

This is a summary of research studies (known as clinical trials) called SPIRIT 1 and SPIRIT 2. The SPIRIT 1 and SPIRIT 2 studies compared how well a medicine called relugolix combination therapy worked in relieving pain in women with moderate to severe endometriosis compared to a placebo, a pill with no active medication. Endometriosis occurs when tissue similar to what normally lines the uterus grows in other places, such as the ovaries, fallopian tubes, and bowels
17th Jan 2024

Relugolix combination therapy for the treatment of pain associated endometriosis: a plain language summary

This is a plain language summary of two articles describing the results from a study called BLC2001. The study examined the effect of a medication called erdafitinib on participants with a type of cancer known as urothelial carcinoma that had either spread beyond the bladder or urinary tract into surrounding organs and/or nearby muscles (locally advanced) and was not removable by surgery (unresectable) or had spread to other parts of the body (metastatic)
3rd Nov 2023

A plain language summary of erdafitinib in locally advanced or metastatic urothelial carcinoma: a phase 2 study with a long term follow-up

This is a plain language summary of an article originally published in the journal Blood Pressure Monitoring. Vibegron is a medicine that was approved by the US Food and Drug Administration (also called FDA) in 2020 for treatment of overactive bladder, a condition that causes a frequent and urgent need to urinate. This study took place before the medicine was approved to look at whether vibegron affects blood pressure or heart rate
13th Sep 2023

The effect of vibegron on the blood pressure and heart rate in people with overactive bladder: a plain language summary

25th Nov 2022

Which traits affect how long patients with advanced prostate cancer live when treated with enzalutamide?

25th Nov 2022

Does race make a difference in how long men with advanced prostate cancer live when treated with abiraterone or enzalutamide?

20th Sep 2022

Plain language summary of a study looking at heart muscle thickness and kidney function in women with Fabry disease who received agalsidase beta treatment

22nd Aug 2022

Plain language summary of the design of the TALAPRO-2 study comparing talazoparib and enzalutamide versus enzalutamide and placebo in men with metastatic castration-resistant prostate cancer

28th Jul 2022

A plain language summary of the likelihood of symptom relief for patients taking fesoterodine for overactive bladder

15th Jun 2022

Darolutamide and survival in metastatic, hormone-sensitive prostate cancer: a patient and caregiver perspective and plain language summary of the ARASENS trial

20th May 2022

Plain language summary of the HERO study comparing relugolix with leuprolide for men with advanced prostate cancer

9th Feb 2021

Darolutamide and survival in nonmetastatic, castration-resistant prostate cancer: a patient perspective of the ARAMIS trial

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