Plain language summary: effectiveness and safety of gepotidacin, a new oral antibiotic, versus nitrofurantoin, a commonly used antibiotic, for treating uncomplicated urinary tract infections
This Plain Language Summary of Publication article (PLSP) from Future Microbiology, findings from the EAGLE-2 and EAGLE-3 studies, which compared gepotidacin, a new oral antibiotic, with nitrofurantoin, a standard treatment for uncomplicated urinary tract infections (uUTIs). The studies included females aged 12 and older across 15 countries, evaluating treatment success, symptom resolution, and side effects.
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This PLSP is based on an article called ‘Oral gepotidacin versus nitrofurantoin in patients with uncomplicated urinary tract infection (EAGLE-2 and EAGLE-3): two randomised, controlled, double-blind, double-dummy, phase 3, non-inferiority trials’ and was published in the Lancet.
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