Plain language summary: comparing the effects of changing versus continuing blood thinners in people with atrial fibrillation

This Plain Language Summary of Publication article (PLSP) from Future Cardiology describes a real-world study examining patients with non-valvular atrial fibrillation who either continued their initial blood thinner (apixaban or rivaroxaban) or switched to a different one. The research aimed to determine how switching medications affects stroke risk and bleeding complications, addressing an important evidence gap since patients often change treatments for medical or practical reasons despite limited data on the clinical outcomes of such switches.

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This PLSP is based on an article called ‘Clinical Impact of Switching or Continuation of Apixaban or Rivaroxaban among Patients with Non-Valvular Atrial Fibrillation’ and was published in the Journal of Clinical Medicine.

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• Acute coronary syndromes
• Atrial fibrillation
• Stroke
• Thrombosis
• Valvular disease