A plain language summary of the LUMINA-1 study: bone imaging in patients with fibrodysplasia ossificans progressiva

This Plain Language Summary of Publication article (PLSP) from Future Rare Diseases describes a study called LUMINA-1. The study looked at two things:

1. How effective an investigational drug called garetosmab worked in participants with fibrodysplasia ossificans progressiva (FOP). FOP is a rare genetic disease where muscle and connective tissue are replaced by bone.
2. The second analysis looked at how well two types of bone imaging scans worked.

Visit the site using this link to read the article.

This PLSP is based on an article called ‘Comparison of PET plus CT versus CT only in the assessment of new heterotopic ossification bone lesions inpatients with fibrodysplasia ossificans progressiva’ and was published in Bone.

Visit ScienceDirect using the link to read the original article.

• computed tomography
• fibrodysplasia ossificans progressiva
• garetosmab
• heterotopic ossification
• lay summary
• plain language summary
• positron emission tomography