A plain language summary of bronchiectasis in cystic fibrosis and a potential new treatment with cathepsin C inhibitors

This Plain Language Summary of Publication article (PLSP) from Future Rare Diseases, explains how bronchiectasis develops in people with cystic fibrosis (CF), a rare genetic disease affecting the lungs. It explores the role of the immune system, particularly neutrophils, in this condition. The summary also highlights potential new treatments targeting neutrophils that are being studied for bronchiectasis in CF.

Visit the site using this link to read the article.

This PLSP is based on an article called ‘Neutrophil serine proteases in cystic fibrosis: role in disease pathogenesis and rationale as a therapeutic target’ and was published in European Respiratory Journal. 

Visit ERS Publications using the link to read the original article.

• bronchiectasis
• cathepsin C inhibitors
• Cystic fibrosis
• neutrophil serine proteases
• neutrophilic inflammation
• Pathophysiology
• Respiratory disorders
• treatments in development