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diarrhea

24th Jan 2025

Managing gastrointestinal comorbidities with or without trofinetide use in Rett syndrome: a plain language summary

Rett syndrome is a rare genetic disorder that affects the way the brain develops. The medication trofinetide (DAYBUE™) was studied in a large clinical trial called LAVENDER, where it showed a benefit in reducing symptoms of Rett syndrome versus placebo (placebo did not contain medication but looked the same as trofinetide and was taken in the same way). The most common side effect in the trial was diarrhea (frequent and/or watery bowel movements). In order to help caregivers and healthcare providers, experts created recommendations on how to prevent and manage diarrhea if it occurs during trofinetide treatment

31st Jul 2023

diarrhea

Managing gastrointestinal comorbidities with or without trofinetide use in Rett syndrome: a plain language summary

Plain Language Summary: recommendations for managing diarrhea caused by trofinetide use in individuals with Rett Syndrome