Managing gastrointestinal comorbidities with or without trofinetide use in Rett syndrome: a plain language summary
This Plain Language Summary of Publication article (PLSP) from Future Rare Diseases, highlights Rett syndrome, a rare brain disorder often associated with gastrointestinal problems like constipation. The medication trofinetide (DAYBUE™) has shown benefits in reducing some neurological symptoms of Rett syndrome during clinical trials, though common side effects included diarrhea and vomiting. Experts have developed recommendations to help caregivers and healthcare providers prevent and manage gastrointestinal issues, whether or not individuals are treated with trofinetide.
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This PLSP is based on an article called ‘Recommendations for the management of gastrointestinal comorbidities with or without trofinetide use in Rett syndrome’ and was published in the Expert Review of Gastroenterology & Hepatology.
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