This Plain Language Summary of publication article (PLSP) from Future Oncology covers the phase 3 CARTITUDE-4 clinical trial, which compared ciltacabtagene autoleucel (cilta-cel) with standard treatments for multiple myeloma. Participants, who had not responded to 1 to 3 prior treatments, including lenalidomide, were studied to assess the effectiveness of cilta-cel in improving their condition.

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This PLSP is based on an article called ‘Cilta-cel or Standard Care in Lenalidomide-Refractory Multiple Myeloma’ and was published in The New England Journal of Medicine. 

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