This summary explains the findings from a recent investigation that  combined  the  results  of  over  1000  people  from  three  clinical studies to understand the safety of evobrutinib.Evobrutinib  is  an  oral  medication  (taken  by  mouth),  being  researched  as  a  potential  treatment  for  multiple  sclerosis  (MS).  This  medication  was  also  investigated  in  rheumatoid  arthritis (RA) and systemic lupus erythematosus (SLE).Over  1000  people  have  taken  evobrutinib  as  part  of  three  separate  phase  2  clinical  studies.  These  studies  looked  at  how much of the drug should be taken, how safe the drug is, and how well it might work for treating a certain medical condition.This Plain Language Summary of Publication from Neurodegenerative Disease Management summarises the findings from three studies which looked at the safety of the medication evobrutinib. The research shows encouraging results that can inform further research into using the medication to treat multiple sclerosis.

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This summary is based on an original article published in the Journal of Neurology, Neurosurgery & Psychiatry. The original article is called ‘Characterisation of the safety profile of evobrutinib in over 1000 patients from phase II clinical trials in multiple sclerosis, rheumatoid arthritis and systemic lupus erythematosus: an integrated safety analysis’. You can read it here.